Article
COVID-19 variants that escape vaccine immunity: Global and Indian context-are more vaccines needed?
Journal of biosciences - 1 Jan 2021
Deb Bijayeeta, Vilvadrinath Ramya, Goel Suchi
Abstract excerpt
The COVID-19 pandemic that emerged around December 2019 claimed millions of lives. For vaccine development, S protein on viral envelope that binds to ACE2 receptor on cells for entry was identified as vaccine candidate. S protein consists of Receptor Binding Motif (RBM) in the S1 subunit followed by the S2 subunit with an intermediate furin cleavage site. A stabilized version of S protein with 2 proline residues...
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