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Article

Do Genetic Variants Modify the Effect of Smoking on Risk of Preeclampsia in Pregnancy?

American journal of perinatology - 1 Jan 2024

Bauer Anna E, Avery Christy L, Shi Min, Weinberg Clarice R, Olshan Andrew F, Harmon Quaker E, Luo Jingchun, Yang Jenny, Manuck Tracy, Wu Michael C, Klungsøyr Kari, Trogstad Lill, Magnus Per, Engel Stephanie M

Abstract excerpt

OBJECTIVE: Maternal smoking is associated with as much as a 50% reduced risk of preeclampsia, despite increasing risk of other poor pregnancy outcomes that often co-occur with preeclampsia, such as preterm birth and fetal growth restriction. Researchers have long sought to understand whether this perplexing association is biologically based, or a result of noncausal mechanisms. We examined whether...

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Identifiers

PMID: 34839469
DOI: 10.1055/s-0041-1740072
PMCID: PMC10127527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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