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Article

Subtyping non-small cell lung cancer by histology-guided spatial metabolomics.

Journal of cancer research and clinical oncology - 1 Feb 2022

Neumann Judith Martha, Freitag Hinrich, Hartmann Jasmin Saskia, Niehaus Karsten, Galanis Michail, Griesshammer Martin, Kellner Udo, Bednarz Hanna

Abstract excerpt

PURPOSE: Most cancer-related deaths worldwide are associated with lung cancer. Subtyping of non-small cell lung cancer (NSCLC) into adenocarcinoma (AC) and squamous cell carcinoma (SqCC) is of importance, as therapy regimes differ. However, conventional staining and immunohistochemistry have their limitations. Therefore, a spatial metabolomics approach was aimed to detect differences between subtypes and to...

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Identifiers

PMID: 34839410
DOI: 10.1007/s00432-021-03834-w
PMCID: PMC8800912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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