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Article

Association of polymorphisms in MALAT1 with risk of coronary atherosclerotic heart disease in a Chinese population.

Lipids in health and disease - 10 Apr 2018

Wang Genan, Li Yaxiong, Peng Yong, Tang Jian, Li Hua

Abstract excerpt

BACKGROUND: Metastasis associated lung adenocarcinoma transcript 1 (MALAT1) plays an important role in vascular remodeling. Down-regulation of MALAT1 can inhibit the proliferation of vascular endothelial cells and vascular smooth muscle cells, reduce cardiomyocyte apoptosis and improve left ventricular function, which is closely linked to numerous pathological processes such as coronary atherosclerotic heart...

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Identifiers

PMID: 29631611
DOI: 10.1186/s12944-018-0728-2
PMCID: PMC5891990

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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