Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Controlled Growth Factor Delivery and Cyclic Stretch Induces a Smooth Muscle Cell-like Phenotype in Adipose-Derived Stem Cells.

Cells - 11 Nov 2021

Walters Brandan, Turner Paul A, Rolauffs Bernd, Hart Melanie L, Stegemann Jan P

Abstract excerpt

Adipose-derived stem cells (ASCs) are an abundant and easily accessible multipotent stem cell source with potential application in smooth muscle regeneration strategies. In 3D collagen hydrogels, we investigated whether sustained release of growth factors (GF) PDGF-AB and TGF-β1 from GF-loaded microspheres could induce a smooth muscle cell (SMC) phenotype in ASCs, and if the addition of uniaxial cyclic stretch...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioreactors
Share to Cell Shape
Share to Cross-Linking Reagents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gelatin

Share to Microspheres

Share to Myocytes, Smooth Muscle

Share to Stress, Mechanical

Source

Open in PubMed Open full text

Identifiers

PMID: 34831345
DOI: 10.3390/cells10113123
PMCID: PMC8624888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Controlled Growth Factor Delivery and Cyclic Stretch Induces a Smooth Muscle Cell-like Phenotype in Adipose-Derived Stem Cells.PMID 34831345Read ↗

Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition.Semantic proximity Read ↗

Efficient generation of smooth muscle cells from adipose-derived stromal cells by 3D mechanical stimulation can substitute the use of growth factors in vascular tissue engineering.Semantic proximity Read ↗

Adipose-derived stem cells loaded photocurable and bioprintable bioinks composed of GelMA, HAMA and PEGDA crosslinker to differentiate into smooth muscle phenotype.Semantic proximity Read ↗

Generation and Characterization of Human Mesenchymal Stem Cell-Derived Smooth Muscle CellsSemantic proximity Read ↗

Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation.Semantic proximity Read ↗

Differentiation of adult stem cells into smooth muscle for vascular tissue engineering.Semantic proximity Read ↗

Adipose derived stem cells and smooth muscle cells: implications for regenerative medicine.Semantic proximity Read ↗

Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem CellsSemantic proximity Read ↗

Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype.Semantic proximity Read ↗

Adipose-derived stem cell delivery into collagen gels using chitosan microspheres.Semantic proximity Read ↗

Human mesenchymal stem cells cultured on silk hydrogels with variable stiffness and growth factor differentiate into mature smooth muscle cell phenotype.Semantic proximity Read ↗

Scaffolds for engineering smooth muscle under cyclic mechanical strain conditions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.