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Small Extracellular Vesicles in Transplant Rejection

3 Nov 2021

Abstract excerpt

Small extracellular vesicles (sEV), which are released to body fluids (e.g., serum, urine) by all types of human cells, may stimulate or inhibit the innate and adaptive immune response through multiple mechanisms. Exosomes or sEV have on their surface many key receptors of immune response, including major histocompatibility complex (MHC) components, identical to their cellular origin. They also exhibit an ability...

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PMID: 34831212
DOI: 10.3390/cells10112989

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