Article
Computational Insights into the Binding Mechanism of OxyS sRNA with Chaperone Protein Hfq.
Biomolecules - 8 Nov 2021
Li Mengxin, Cong Yalong, Qi Yifei, Zhang John Z H
Abstract excerpt
Under the oxidative stress condition, the small RNA (sRNA) OxyS that acts as essential post-transcriptional regulators of gene expression is produced and plays a regulatory function with the assistance of the RNA chaperone Hfq protein. Interestingly, experimental studies found that the N48A mutation of Hfq protein could enhance the binding affinity with OxyS while resulting in the defection of gene regulation....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.