Article
Assessing Cardiac Amyloidosis Subtypes by Unsupervised Phenotype Clustering Analysis.
Journal of the American College of Cardiology - 30 Nov 2021
Bonnefous Louis, Kharoubi Mounira, Bézard Mélanie, Oghina Silvia, Le Bras Fabien, Poullot Elsa, Molinier-Frenkel Valérie, Fanen Pascale, Deux Jean-François, Audard Vincent, Itti Emmanuel, Damy Thibaud, Audureau Etienne
Abstract excerpt
BACKGROUND: Cardiac amyloidosis (CA) is a set of amyloid diseases with usually predominant cardiac symptoms, including light-chain amyloidosis (AL), hereditary variant transthyretin amyloidosis (ATTRv), and wild-type transthyretin amyloidosis (ATTRwt). CA are characterized by high heterogeneity in phenotypes leading to diagnosis delay and worsened outcomes. OBJECTIVES: The authors used clustering analysis to...
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