Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uncovering the Bioactive Potential of a Cyanobacterial Natural Products Library Aided by Untargeted Metabolomics

12 Nov 2021

Abstract excerpt

The Blue Biotechnology and Ecotoxicology Culture Collection (LEGE-CC) holds a vast number of cyanobacteria whose chemical richness is still largely unknown. To expedite its bioactivity screening we developed a natural products library. Sixty strains and four environmental samples were chromatographed, using a semiautomatic HPLC system, yielding 512 fractions that were tested for their cytotoxic activity against...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Metabolomics and Mass Spectrometry Studies
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34822504
DOI: 10.3390/md19110633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncovering the Bioactive Potential of a Cyanobacterial Natural Products Library Aided by Untargeted MetabolomicsPMID 34822504Read ↗

Metabolomics and genomics in natural products research: complementary tools for targeting new chemical entitiesSemantic proximity Read ↗

Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene clusterSemantic proximity Read ↗

Metabolomic Characterization of a cf. Neolyngbya Cyanobacterium from the South China Sea Reveals Wenchangamide A, a Lipopeptide with In Vitro Apoptotic Potential in Colon Cancer CellsSemantic proximity Read ↗

Unlocking Biological Activity and Metabolomics Insights: Primary Screening of Cyanobacterial Biomass from a Tropical ReservoirSemantic proximity Read ↗

Triumphs and Challenges of Natural Product Discovery in the Postgenomic EraSemantic proximity Read ↗

Genomic and Chemical Decryption of the Bacteroidetes Phylum for Its Potential to Biosynthesize Natural ProductsSemantic proximity Read ↗

Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols.Semantic proximity Read ↗

Metabolomics‐based chemotaxonomy of root endophytic fungi for natural products discoverySemantic proximity Read ↗

Phenotypic screening in zebrafish larvae identifies promising cyanobacterial strains and pheophorbide a as insulin mimetics.Semantic proximity Read ↗

Colombian cyanobacteria with cytotoxic activity in cancer cell linesSemantic proximity Read ↗

Expanding CyanoHAB Monitoring: New Micropeptins and Generalizable MS/MS Workflows for the Annotation of Cyanopeptide ClassesSemantic proximity Read ↗

Novel bioactive natural products from bacteria via bioprospecting, genome mining and metabolic engineeringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.