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Article

Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models.

Scientific reports - 24 Nov 2021

Siegerist Florian, Lange Tim, Iervolino Anna, Koppe Thor Magnus, Zhou Weibin, Capasso Giovambattista, Endlich Karlhans, Endlich Nicole

Abstract excerpt

The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot process architecture, which inevitably leads to a reduced kidney filtration and total loss of kidney function. It could have been shown that microRNAs (miRs) play a pivotal role in the pathogenesis of podocyte-associated kidney diseases. Due to their fully functioning pronephric kidney,...

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Identifiers

PMID: 34819534
DOI: 10.1038/s41598-021-00075-2
PMCID: PMC8613261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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