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Involvement of immune system and Epithelial–Mesenchymal-Transition in increased invasiveness of clustered circulatory tumor cells in breast cancer

20 Nov 2021

Abstract excerpt

BACKGROUND: Circulating tumor cells (CTCs) are the critical initiators of distant metastasis formation. In which, the reciprocal interplay among different metastatic pathways and their metastasis driver genes which promote survival of CTCs is not well introduced using network approaches. METHODS: Here, to investigate the unknown pathways of single/cluster CTCs, the co-expression network was reconstructed, using...

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PMID: 34801010
DOI: 10.1186/s12920-021-01112-9

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