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Article

Drug resistance in Candida albicans isolates and related changes in the structural domain of Mdr1 protein

4 Nov 2021

Abstract excerpt

BACKGROUND: The increasing azole drug resistance in fungal pathogens poses a pressing threat to global health care. The coexistence of drug-resistant Candida albicans with tuberculosis patients and the failure of several drugs to treat C. albicans infection extend hospital stay, economic burden, and death. The misuse or abuse of azole-derived antifungals, chronic use of TB drugs, different immune-suppressive...

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PMID: 34794907
DOI: 10.1016/j.jiph.2021.11.002

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