Selection shapes the landscape of functional variation in wild house mice.

Abstract excerpt

BACKGROUND: Through human-aided dispersal over the last ~ 10,000 years, house mice (Mus musculus) have recently colonized diverse habitats across the globe, promoting the emergence of new traits that confer adaptive advantages in distinct environments. Despite their status as the premier mammalian model system, the impact of this demographic and selective history on the global patterning of disease-relevant trait...

Topics

• Adaptation, Physiological
• Animals
• Genetic Variation
• Genome
• Mammals
• Mice
• Phenotype
• Selection, Genetic