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Cluster analysis of clinical manifestations assigns systemic lupus erythematosus-phenotype subgroups: A multicentre study on 440 patients.

Joint bone spine - 1 Dec 2024

Mariette Fanny, Le Guern Véronique, Nguyen Yann, Yelnik Cécile, Morel Nathalie, Hachulla Eric, Lambert Marc, Guettrot-Imbert Gaëlle, Mouthon Luc, Ebbo Mikael, Costedoat-Chalumeau Nathalie

Abstract excerpt

OBJECTIVE: Systemic lupus erythematous (SLE) is a heterogenous disease characterised by a large panel of autoantibodies and a wide spectrum of clinical signs and symptoms that engender different outcomes. We aimed to identify distinct, homogeneous SLE patients' phenotypes. METHODS: This retrospective study enrolled SLE patients meeting the Systemic Lupus International Collaborating Clinics (SLICC) classification...

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PMID: 38972539
DOI: 10.1016/j.jbspin.2024.105760

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