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Article

Volumetric response and pattern of failure of histone altered high grade glioma in adults following management with radiation therapy.

Journal of neuro-oncology - 1 May 2023

Knight A, Horsley P, Yuile A, Yim J, Suh M, Venketesha V, Kastelan M, Wheeler H, Back M

Abstract excerpt

PURPOSE: H3K27M- and H3G34R-mutant gliomas are recently-classified subgroups of high-grade gliomas (HGGs) affecting younger adults. This study aimed to describe patterns of infiltration and failure, and the volumetric response of these tumours to radiotherapy. METHODS: Patients with histone-mutant gliomas aged 16-50 years, managed from 2009 to 2021 were identified and clinical, radiological and histopathological...

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Identifiers

PMID: 37184742
DOI: 10.1007/s11060-023-04332-4

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