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Article

Reduced levels of convalescent neutralizing antibodies against SARS-CoV-2 B.1+L249S+E484K lineage.

Virus research - 15 Jan 2022

Álvarez-Díaz Diego A, Laiton-Donato Katherine, Torres-García Orlando Alfredo, Ruiz-Moreno Hector Alejandro, Franco-Muñoz Carlos, Beltran Maria Angie, Mercado-Reyes Marcela, Rueda Miguel Germán, Muñoz Ana Luisa

Abstract excerpt

The E484K mutation at the SARS-CoV-2 Spike protein emerged independently in different variants around the world and has been widely associated with immune escape from neutralizing antibodies generated during previous infection or vaccination. In this work, the B.1 + L249S+E484K lineage was isolated along with A.1, B.1.420, and B.1.111 SARS-CoV-2 lineages without the E484K mutation and the neutralizing titer of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34780883
DOI: 10.1016/j.virusres.2021.198629
PMCID: PMC8585963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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