Article
Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol.
PLoS pathogens - 1 Nov 2021
Verner Zdeněk, Žárský Vojtěch, Le Tien, Narayanasamy Ravi Kumar, Rada Petr, Rozbeský Daniel, Makki Abhijith, Belišová Darja, Hrdý Ivan, Vancová Marie, Lender Corinna, König Constantin, Bruchhaus Iris, Tachezy Jan
Abstract excerpt
Entamoeba histolytica is believed to be devoid of peroxisomes, like most anaerobic protists. In this work, we provided the first evidence that peroxisomes are present in E. histolytica, although only seven proteins responsible for peroxisome biogenesis (peroxins) were identified (Pex1, Pex6, Pex5, Pex11, Pex14, Pex16, and Pex19). Targeting matrix proteins to peroxisomes is reduced to the PTS1-dependent pathway...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.