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Article

The Minimal Proteome in the Reduced Mitochondrion of the Parasitic Protist Giardia intestinalis

24 Feb 2011

Abstract excerpt

The mitosomes of Giardia intestinalis are thought to be mitochondria highly-reduced in response to the oxygen-poor niche. We performed a quantitative proteomic assessment of Giardia mitosomes to increase understanding of the function and evolutionary origin of these enigmatic organelles. Mitosome-enriched fractions were obtained from cell homogenate using Optiprep gradient centrifugation. To distinguish mitosomal...

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PMID: 21390322
DOI: 10.1371/journal.pone.0017285

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