Article
Cost-utility analysis of risk-reducing strategies to prevent breast and ovarian cancer in BRCA-mutation carriers in Switzerland.
The European journal of health economics : HEPAC : health economics in prevention and care - 1 Jul 2022
Bommer Claudine, Lupatsch Judith, Bürki Nicole, Schwenkglenks Matthias
Abstract excerpt
OBJECTIVE: We aimed to identify the most cost-effective of all prophylactic measures available in Switzerland for women not yet affected by breast and ovarian cancer who tested positive for a BRCA1/2 mutation. METHODS: Prophylactic bilateral mastectomy (PBM), salpingo-oophorectomy (PBSO), combined PBM&PBSO and chemoprevention (CP) initiated at age 40 years were compared with intensified surveillance (IS). A...
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