Article
Distribution, phenotype, functional and clinical relevance of CD8+CD103+ tissue-resident memory T cells in human gastric cancer.
Cancer immunology, immunotherapy : CII - 1 Jul 2022
Shen Yang, Li Xiao-Long, Li Yu-Xian, Shan Zhi-Guo, Zhao Yong-Liang, Cheng Ping, Zhao Zhuo, Zhang Jin-Yu, Chen Weisan, Zhuang Yuan, Ma Dai-Yuan, Zou Quan-Ming, Qiu Yuan, Peng Liu-Sheng
Abstract excerpt
CD8+CD103+ tissue-resident memory T cells (TRMs) are involved in tumor immune response and linked to favorable clinical outcome in human cancer. However, the distribution, phenotype, functional properties and clinical relevance of these cells in gastric cancer (GC) remain elusive. Here, our data show that, in comparison to non-tumor tissues, the percentages of CD8+CD103+ TRMs in tumors are significantly...
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