Article
Origins and evolution of extreme life span in Pacific Ocean rockfishes.
Science (New York, N.Y.) - 12 Nov 2021
Kolora Sree Rohit Raj, Owens Gregory L, Vazquez Juan Manuel, Stubbs Alexander, Chatla Kamalakar, Jainese Conner, Seeto Katelin, McCrea Merit, Sandel Michael W, Vianna Juliana A, Maslenikov Katherine, Bachtrog Doris, Orr James W, Love Milton, Sudmant Peter H
Abstract excerpt
Pacific Ocean rockfishes (genus Sebastes) exhibit extreme variation in life span, with some species being among the most long-lived extant vertebrates. We de novo assembled the genomes of 88 rockfish species and from these identified repeated signatures of positive selection in DNA repair pathways in long-lived taxa and 137 longevity-associated genes with direct effects on life span through insulin signaling and...
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