Article
Evolutionary adaptation revealed by comparative genome analysis of woolly mammoths and elephants.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Aug 2017
Smith Sean D, Kawash Joseph K, Karaiskos Spyros, Biluck Ian, Grigoriev Andrey
Abstract excerpt
Comparative genomics studies typically limit their focus to single nucleotide variants (SNVs) and that was the case for previous comparisons of woolly mammoth genomes. We extended the analysis to systematically identify not only SNVs but also larger structural variants (SVs) and indels and found multiple mammoth-specific deletions and duplications affecting exons or even complete genes. The most prominent SV...
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