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Article

Genome Instability-Related miRNAs Predict Survival, Immune Landscape, and Immunotherapy Responses in Gastric Cancer.

Journal of immunology research - 1 Jan 2021

Liu Yaqiong, Cheng Lin, Huang Wei, Cheng Xin, Peng Weijun, Shi Dazun

Abstract excerpt

BACKGROUND: Increasing evidence suggests that microRNAs (miRNAs) are involved in genome instability (GI) and drive the occurrence of tumors. However, the role of GI-related miRNAs in gastric cancer (GC) remains largely unknown. Herein, we developed a novel GI-related miRNA signature (GIMiSig) and further investigated its role in prognosis, the immune landscape, and immunotherapy responses in GC patients. METHODS:...

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Biomarkers, Tumor
Carrier Proteins
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Genomic Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stomach Neoplasms

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Identifiers

PMID: 34761007
DOI: 10.1155/2021/2048833
PMCID: PMC8575650

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