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Culture-Independent Detection of Poliovirus in Stool Samples by Direct RNA Extraction

10 Nov 2021

Abstract excerpt

Successfully identifying poliovirus from acute flaccid paralysis (AFP) cases is a vital role of the Global Polio Laboratory Network to achieve the goals of the Global Polio Eradication Initiative. Currently, laboratory surveillance relies on virus isolation by cell culture to test for PV present in stool samples. Although this method can identify polioviruses, laboratories must switch to culture-independent...

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PMID: 34756088
DOI: 10.1128/spectrum.00668-21

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