Article
Non-synonymous mutations of SARS-CoV-2 leads epitope loss and segregates its variants.
Microbes and infection - 1 Jan 2000
Gupta Aayatti Mallick, Chakrabarti Jaydeb, Mandal Sukhendu
Abstract excerpt
The non-synonymous mutations of SARS-CoV-2 isolated from across the world have been identified during the last few months. The surface glycoprotein spike of SARS-CoV-2 forms the most important hotspot for amino acid alterations followed by the ORF1a/ORF1ab poly-proteins. It is evident that the D614G mutation in spike glycoprotein and P4715L in RdRp is the important determinant of SARS-CoV-2 evolution since its...
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