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Article

Association between somatic RET mutations and clinical and genetic characteristics in patients with metastatic colorectal cancer.

Cancer medicine - 1 Dec 2021

Yang Yuan-Zhong, Hu Wan-Ming, Xia Liang-Ping, He Wen-Zhuo

Abstract excerpt

BACKGROUND: Rearranged during transfection (RET) is a targetable oncogene. RET fusions have been reported in patients with metastatic colorectal cancer (mCRC). However, RET mutations in mCRC are less studied. Here, we aimed to characterize the clinical, pathological, and molecular landscape of RET-mutated mCRC. METHODS: Five hundred and eighty-two patients were included in this study. Next-generation sequencing...

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Identifiers

PMID: 34741450
DOI: 10.1002/cam4.4400
PMCID: PMC8683541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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