Article
REToma: a cancer subtype with a shared driver oncogene.
Carcinogenesis - 22 Apr 2020
Kohno Takashi, Tabata Junya, Nakaoku Takashi
Abstract excerpt
RET (REarranged during Transfection), which encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor, plays a role as driver oncogene in a variety of human cancers. Fusion of RET with several partner genes has been detected in papillary thyroid, lung, colorectal, pancreatic and breast cancers, and tyrosine kinase inhibitors (TKIs) for RET (particularly RET-specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
