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Article

Identification and characterization of RET fusions in advanced colorectal cancer.

Oncotarget - 6 Oct 2015

Le Rolle Anne-France, Klempner Samuel J, Garrett Christopher R, Seery Tara, Sanford Eric M, Balasubramanian Sohail, Ross Jeffrey S, Stephens Philip J, Miller Vincent A, Ali Siraj M, Chiu Vi K

Abstract excerpt

There is an unmet clinical need for molecularly directed therapies available for metastatic colorectal cancer. Comprehensive genomic profiling has the potential to identify actionable genomic alterations in colorectal cancer. Through comprehensive genomic profiling we prospectively identified 6 RET fusion kinases, including two novel fusions of CCDC6-RET and NCOA4-RET, in metastatic colorectal cancer (CRC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26078337
DOI: 10.18632/oncotarget.4325
PMCID: PMC4745701

Genes

RET
BRAF
CCDC6
KRAS
NCOA4
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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