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Article

An SNP reducing SNORD105 and PPAN expression decreases the risk of hepatocellular carcinoma in a Chinese population.

Journal of clinical laboratory analysis - 1 Dec 2021

Chen Xuekun, Zhang Qing, Yang Zhenzhen, Yu Huan, Qu Yiling, Tan Rui, Gao Yuzhen, He Yan, Li Lijuan

Abstract excerpt

BACKGROUND: With hepatocellular carcinoma (HCC) becoming a heavy disease burden in China, it is particular to reveal its pathological mechanism. Recent researches have indicated that small nucleolar RNAs (snoRNAs) may be involved in various cancers including HCC. Polymorphisms within snoRNAs may affect its function or expression level, and even its host gene, then produce series of effects related to itself or...

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Identifiers

PMID: 34741342
DOI: 10.1002/jcla.24095
PMCID: PMC8649375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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