Article
CYP2D6 Genotyping and Antipsychotic-Associated Extrapyramidal Adverse Effects in a Randomized Trial of Aripiprazole Versus Quetiapine Extended Release in Children and Adolescents, Aged 12-17 Years, With First Episode Psychosis.
Journal of clinical psychopharmacology - 1 Jan 2000
Rudå Ditte, Jensen Karsten Gjessing, Decara Marie Stentebjerg, Klauber Dea Gowers, Fagerlund Birgitte, Møllegaard Jens Richardt, Linnet Kristian, Werge Thomas, Correll Christoph U, Fink-Jensen Anders, Jürgens Gesche, Pagsberg Anne Katrine
Abstract excerpt
PURPOSE/BACKGROUND: The aim of this study was to examine the association between genetically predicted CYP2D6 phenotypes and extrapyramidal symptoms (EPSs). METHODS/PROCEDURES: Data from the Tolerability and Efficacy of Antipsychotics trial of adolescents with first-episode psychosis randomized to aripiprazole versus quetiapine extended release were studied. Extrapyramidal symptom assessments included the...
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