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Article

Tissue, age, sex, and disease patterns of matrisome expression in GTEx transcriptome data.

Scientific reports - 3 Nov 2021

Nieuwenhuis Tim O, Rosenberg Avi Z, McCall Matthew N, Halushka Marc K

Abstract excerpt

The extracellular matrix (ECM) has historically been explored through proteomic methods. Whether or not global transcriptomics can yield meaningful information on the human matrisome is unknown. Gene expression data from 17,382 samples across 52 tissues, were obtained from the Genotype-Tissue Expression (GTEx) project. Additional datasets were obtained from The Cancer Genome Atlas (TCGA) program and the Gene...

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PMID: 34732773
DOI: 10.1038/s41598-021-00943-x
PMCID: PMC8566510

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