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Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2021

Bazhenova Lyudmila, Minchom Anna, Viteri Santiago, Bauml Joshua M, Ou Sai-Hong Ignatius, Gadgeel Shirish M, Trigo José Manuel, Backenroth Daniel, Li Tracy, Londhe Anil, Mahadevia Parthiv, Girard Nicolas

Abstract excerpt

INTRODUCTION: Real-world clinical outcomes in patients with advanced NSCLC harboring EGFR exon 20 insertion (exon20ins) mutations have not been extensively studied. We conducted a retrospective cohort study to assess the clinical outcomes of EGFR exon20ins compared with common EGFR (cEGFR) mutations. METHODS: Adults with advanced NSCLC harboring any EGFR mutations in the NSCLC Flatiron registry (2011 through May...

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PMID: 34818606
DOI: 10.1016/j.lungcan.2021.10.020

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