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Article

Link between obsessive-compulsive disorder and polymorphisms in HDAC genes.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jan 2000

Dondu Ayse, Caliskan Metin, Orenay-Boyacioglu Seda

Abstract excerpt

OBJECTIVE: Recently, epigenetic mechanisms related to histone modifications including histone deacetylation (HDAC) have been emphasized in psychiatric diseases. Few studies have investigated the relationship of HDAC gene variations to psychiatric diseases, but these gene variations have never been studied in obsessive-compulsive disorder (OCD). The present case-control study aimed to compare symptomatology with...

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PMID: 34730715
DOI: 10.1590/1516-4446-2020-1715
PMCID: PMC9041966

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