[Myelodysplastic syndrome and acut leukaemia].

Abstract excerpt

Myelodysplastic syndrome and acute myeloid leukaemia are neoplastic diseases caused by genetic alterations of the haematopoietic stem cells. Advances in sequencing techniques have led to a profound understanding of the underlying pathogeneses. Somatic mutations and chromosomal aberrations can be found in > 90% of the cases. The improved understanding of the pathogeneses has translated into better risk...

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