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Article

Dissecting the Pathogenesis of Diabetic Retinopathy Based on the Biological ceRNA Network and Genome Variation Disturbance.

Computational and mathematical methods in medicine - 1 Jan 2021

Zhu Xiaodan, Hao Ming, Yu Xinyang, Lin Wenjian, Ma Xuefei, Xu Qian, Cheng Lei, Kuang Hongyu

Abstract excerpt

BACKGROUND: Diabetic retinopathy (DR) is the most important manifestation of diabetic microangiopathy. It is essential to explore the gene regulatory relationship and genomic variation disturbance of biological networks in DR progression. METHODS: In this study, we constructed a comprehensive lncRNA-mRNA ceRNA network of DR procession (CLMN) and explored its topological characteristics. RESULTS: Modular and...

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Identifiers

PMID: 34707685
DOI: 10.1155/2021/9833142
PMCID: PMC8545528

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