Article
Common variable immunodeficiency: an update on etiology and management.
Immunology and allergy clinics of North America - 1 May 2008
Yong Patrick F K, Tarzi Michael, Chua Ignatius, Grimbacher Bodo, Chee Ronnie
Abstract excerpt
Common variable immunodeficiency (CVID) represents a heterogeneous group of primary antibody deficiency disorders characterized by recurrent infection and by inflammatory, granulomatous, and autoimmune complications. Recently, there have been significant advances in understanding the pathogenesis of the disease, with five genetic mutations identified in patients who have a CVID phenotype. Clinical care also has...
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