Article
Epidemiology of mutant Plasmodium falciparum parasites lacking histidine-rich protein 2/3 genes in Eritrea 2 years after switching from HRP2-based RDTs.
Scientific reports - 26 Oct 2021
Mihreteab Selam, Anderson Karen, Pasay Cielo, Smith David, Gatton Michelle L, Cunningham Jane, Berhane Araia, Cheng Qin
Abstract excerpt
Eritrea was the first African country to complete a nationwide switch in 2016 away from HRP2-based RDTs due to high rates of false-negative RDT results caused by Plasmodium falciparum parasites lacking hrp2/hrp3 genes. A cross-sectional survey was conducted during 2019 enrolling symptomatic malaria patients from nine health facilities across three zones consecutively to investigate the epidemiology of P....
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