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Article

Construction and Evaluation of a Tumor Mutation Burden-Related Prognostic Signature for Thyroid Carcinoma.

Computational and mathematical methods in medicine - 1 Jan 2021

Lu Haodong, Liu Qian, Chang Qing, Du Jinghai, Zhang Chunying, Chang Wang, Guo Xin, Hu Yaojie, Liu Shiguang, Tang Guoshuai, Chen Chunyou

Abstract excerpt

Thyroid carcinoma is a type of prevalent cancer. Its prognostic evaluation depends on clinicopathological features. However, such conventional methods are deficient. Based on mRNA, single nucleotide variants (SNV), and clinical information of thyroid carcinoma from The Cancer Genome Atlas (TCGA) database, this study statistically analyzed mutational signature of patients with this disease. Missense mutation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 34697553
DOI: 10.1155/2021/1435827
PMCID: PMC8538398

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