Article
Phylogenomic Analysis of Human Papillomavirus Type 31 and Cervical Carcinogenesis: A Study of 2093 Viral Genomes.
Viruses - 28 Sept 2021
Pinheiro Maisa, Harari Ariana, Schiffman Mark, Clifford Gary M, Chen Zigui, Yeager Meredith, Cullen Michael, Boland Joseph F, Raine-Bennett Tina, Steinberg Mia, Bass Sara, Xiao Yanzi, Tenet Vanessa, Yu Kai, Zhu Bin, Burdett Laurie, Turan Sevilay, Lorey Thomas, Castle Philip E, Wentzensen Nicolas, Burk Robert D, Mirabello Lisa
Abstract excerpt
Human papillomavirus (HPV) type 31 (HPV31) is closely related to the most carcinogenic type, HPV16, but only accounts for 4% of cervical cancer cases worldwide. Viral genetic and epigenetic variations have been associated with carcinogenesis for other high-risk HPV types, but little is known about HPV31. We sequenced 2093 HPV31 viral whole genomes from two large studies, one from the U.S. and one international....
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