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Prediction of Antimicrobial Resistance in Clinical Enterococcus faecium Isolates Using a Rules-Based Analysis of Whole-Genome Sequences

25 Oct 2021

Abstract excerpt

(M) alleles that provide insight into ampicillin and tetracycline class resistance mechanisms. The prediction rules demonstrated generalizability when tested on an external data set. In conclusion, known AMR genes and mutations can predict E. faecium phenotypic susceptibility with high accuracy for most routinely tested antibiotics, providing opportunities for advancing molecular diagnostics.

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Share to Antibiotic Resistance in Bacteria
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Share to Bacterial Identification and Susceptibility Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34694881
DOI: 10.1128/aac.01196-21

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