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Engineered Bacteriophage as a Delivery Vehicle for Antibacterial Protein, SASP

12 Oct 2021

Abstract excerpt

The difficulties in developing novel classes of antibacterials is leading to a resurgence of interest in bacteriophages as therapeutic agents, and in particular engineered phages that can be optimally designed. Here, pre-clinical microbiology assessment is presented of a Staphylococcus aureus phage engineered to deliver a gene encoding an antibacterial small acid soluble spore protein (SASP) and further, rendered...

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PMID: 34681262
DOI: 10.3390/ph14101038

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