Article
Synergistic action of phage phiIPLA-RODI and lytic protein CHAPSH3b: a combination strategy to target Staphylococcus aureus biofilms.
NPJ biofilms and microbiomes - 22 Apr 2021
Duarte Ana Catarina, Fernández Lucía, De Maesschalck Vincent, Gutiérrez Diana, Campelo Ana Belén, Briers Yves, Lavigne Rob, Rodríguez Ana, García Pilar
Abstract excerpt
Staphylococcus aureus is considered a priority pathogen due to its increasing acquisition of antibiotic resistance determinants. Additionally, this microbe has the ability to form recalcitrant biofilms on different biotic and inert surfaces. In this context, bacteriophages and their derived lytic proteins may be a forward-looking strategy to help combat staphylococcal biofilms. However, these antimicrobials...
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