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Article

The Association of Renal Function and Plasma Metals Modified by EGFR and TNF-α Gene Polymorphisms in Metal Industrial Workers and General Population.

International journal of environmental research and public health - 25 Aug 2021

Chen Tzu-Hua, Huang Joh-Jong, Lee Hsiang-Ying, Kung Wei-Shyang, Luo Kuei-Hau, Lu Jia-Yi, Chuang Hung-Yi

Abstract excerpt

Exposure to metals may be associated with renal function impairment, but the effect modified by genetic polymorphisms was not considered in most studies. Epidermal growth factor receptor (EGFR) and tumor necrotic factor-α (TNF-α) play important roles in renal hemodynamics, and they have been reported to be associated with some renal diseases. The aim of our research is to explore whether genetic variations in...

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Identifiers

PMID: 34501555
DOI: 10.3390/ijerph18178965
PMCID: PMC8431338

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