Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin Resistance

30 Sept 2021

Abstract excerpt

BACKGROUND: Adipose tissue (AT) dysfunction is involved in obesity-related comorbidities. Epigenetic alterations have been recently associated with AT deterioration in obesity conditions. In this work, we profiled the H3K4me3 histone mark in human AT, with special emphasis on the changes in the pattern of histone modification in obesity and insulin resistance (IR). Visceral AT (VAT) was collected and subjected to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34680480
DOI: 10.3390/biomedicines9101363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin ResistancePMID 34680480Read ↗

Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IRSemantic proximity Read ↗

Integrated Multiomic Analysis Reveals the High-Fat Diet Induced Activation of the MAPK Signaling and Inflammation Associated Metabolic Cascades via Histone Modification in Adipose TissuesSemantic proximity Read ↗

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetesSemantic proximity Read ↗

When Genes Wear Marks: Epigenomic Modulation in the Development and Progression of ObesitySemantic proximity Read ↗

Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genesSemantic proximity Read ↗

Genome-Wide Profiling of H3K56 Acetylation and Transcription Factor Binding Sites in Human AdipocytesSemantic proximity Read ↗

Epigenetic regulation of white adipose tissue in the onset of obesity and metabolic diseasesSemantic proximity Read ↗

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetesSemantic proximity Read ↗

Epigenetic modifications in adipose tissue – relation to obesity and diabetesSemantic proximity Read ↗

DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patientsSemantic proximity Read ↗

Histone modifications influence the insulin-signaling genes and are related to insulin resistance in human adipocytesSemantic proximity Read ↗

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.