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Viral Culture Confirmed SARS-CoV-2 Subgenomic RNA Value as a Good Surrogate Marker of Infectivity

20 Oct 2021

Abstract excerpt

Determining SARS-CoV-2 viral infectivity is crucial for patient clinical assessment and isolation decisions. We assessed subgenomic RNA (sgRNA) as a surrogate marker of SARS-CoV-2 infectivity in SARS-CoV-2-positive reverse transcription PCR (RT-PCR) respiratory samples ( n = 105) in comparison with viral culture as the reference standard for virus replication. sgRNA and viral isolation results were concordant in...

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PMID: 34669457
DOI: 10.1128/jcm.01609-21

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