Article
Janus kinase 2 (JAK2) methylation and obesity: A Mendelian randomization study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 29 Nov 2021
Tu Runqi, Liu Xiaotian, Dong Xiaokang, Li Ruiying, Liao Wei, Hou Jian, Mao Zhenxing, Huo Wenqian, Wang Chongjian, Li Yuqian
Abstract excerpt
BACKGROUND AND AIMS: Janus kinase 2 (JAK2) play an important role in the energy metabolism. Whether there is a causal relationship between JAK2 methylation levels and obesity remains unclear. Based on the instrumental variables of 5 SNP sites, this study was aimed to explore the causal relationship between JAK2 methylation levels and obesity by Mendelian randomization analysis. METHODS AND RESULTS: A total of...
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