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Article

Genetic overlap and causality between blood metabolites and migraine.

American journal of human genetics - 4 Nov 2021

Tanha Hamzeh M, Sathyanarayanan Anita, Nyholt Dale R

Abstract excerpt

The availability of genome-wide association studies (GWASs) for human blood metabolome provides an excellent opportunity for studying metabolism in a heritable disease such as migraine. Utilizing GWAS summary statistics, we conduct comprehensive pairwise genetic analyses to estimate polygenic genetic overlap and causality between 316 unique blood metabolite levels and migraine risk. We find significant...

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Share to Causality
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34644541
DOI: 10.1016/j.ajhg.2021.09.011
PMCID: PMC8595896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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