Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding the role of corneal biomechanics-associated genetic variants by bioinformatic analyses.

International ophthalmology - 1 Mar 2022

Sun Xiao, Gao Xiang, Mu Bo-Kun, Wang Yan

Abstract excerpt

PURPOSE: To analyze functions of corneal biomechanical properties (CBP)-related variants as corneal resistance factor (CRF) and corneal hysteresis (CH). METHODS: Related single nucleotide polymorphisms (SNPs) and genes were identified from NHGRI-EBI GWAS catalog, GWASdb v2 and possible data in published studies. HaploReg v4.1 was used to find linkage SNPs. Functional annotations were performed by GWAVA, CADD and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomechanical Phenomena
Share to Computational Biology
Share to Cornea

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 34642840
DOI: 10.1007/s10792-021-02081-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding the role of corneal biomechanics-associated genetic variants by bioinformatic analyses.PMID 34642840Read ↗

Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic etiology of ocular diseases.Semantic proximity Read ↗

Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association StudySemantic proximity Read ↗

Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants.Semantic proximity Read ↗

Causal Effects of Corneal Traits on the risk of Keratoconus Using Genetic InstrumentsSemantic proximity Read ↗

Corneal Biomechanics as a Causal Factor in Myopia and Astigmatism: Evidence from Mendelian RandomizationSemantic proximity Read ↗

Comparison of Corneal Biomechanical Properties between Indian and Chinese Adults.Semantic proximity Read ↗

The Genetic and Epigenetic Architecture of Keratoconus: Emerging Pathways and Clinical Implications.Semantic proximity Read ↗

Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell densitySemantic proximity Read ↗

A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries.Semantic proximity Read ↗

Association of Novel Loci With Keratoconus Susceptibility in a Chinese Genome-Wide Association Study.Semantic proximity Read ↗

Collagen-related genes influence the glaucoma risk factor, central corneal thickness.Semantic proximity Read ↗

Association of shared gene polymorphisms for refraction and axial length with corneal biomechanical properties in children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.