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Article

A germinal center-associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL.

Blood advances - 12 Apr 2022

Miyawaki Kohta, Kato Koji, Sugio Takeshi, Sasaki Kensuke, Miyoshi Hiroaki, Semba Yuichiro, Kikushige Yoshikane, Mori Yasuo, Kunisaki Yuya, Iwasaki Hiromi, Miyamoto Toshihiro, Kuo Frank C, Aster Jon C, Ohshima Koichi, Maeda Takahiro, Akashi Koichi

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common B-cell malignancy, with varying prognosis after the gold standard rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). Several prognostic models have been established by focusing primarily on characteristics of lymphoma cells themselves, including cell-of-origin (COO), genomic alterations, and gene/protein expressions. However,...

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Source

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Identifiers

PMID: 34638128
DOI: 10.1182/bloodadvances.2021004618
PMCID: PMC9006269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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