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Article

Low-frequency and rare coding variants of NUS1 contribute to susceptibility and phenotype of Parkinson's disease.

Neurobiology of aging - 1 Feb 2022

Jiang Li, Mei Jun-Pu, Zhao Yu-Wen, Zhang Rui, Pan Hong-Xu, Yang Yang, Sun Qi-Ying, Xu Qian, Yan Xin-Xiang, Tan Jie-Qiong, Li Jin-Chen, Tang Bei-Sha, Guo Ji-Feng

Abstract excerpt

NUS1 has been recently identified as a candidate gene for Parkinson's disease (PD). Few studies have examined the association of NUS1 variants with PD susceptibility and phenotypes. In the first cohort, whole-exome sequencing was performed to identify variants in NUS1 exon-coding and exon-intron regions in 1542 cases and 1625 controls. 13 variants were totally detected, of which 10 rare variants and 3...

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PMID: 34635350
DOI: 10.1016/j.neurobiolaging.2021.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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